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pentobarbital will lessen the level or impact of hydrocortisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.pentobarbital will lessen the extent or influence of brexpiprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Intently. Double brexpiprazole dose about 1-two